2. PERSONAL HISTORY
Date of Birth: 2 January 1939
Place of Birth: Pampa, Texas
3. EDUCATION
Marine Botany Course, Marine Biological Laboratory, Woods Hole, Massachusetts, Summer, 1959.
B.A. in Botany, with minors in chemistry and zoology. The University of Texas at Austin, June 1961.
Ph.D. in Botany. The University of Texas at Austin, August 1964.
Major Professor: Dr. Harold C. Bold
Dissertation Subject: Comparative Studies of the Algal Genera Tetracystis
and Chlorococcum.
4. POSITIONS HELD
Laboratory Assistant, Department of Botany, University of Texas at Austin, 1959-1961.
Undergraduate Science Research Scholarship (NSF), Department of Botany, University of Texas at Austin, Summers 1960, 1961.
Instructor, High School Biology, Concordia Junior College and High School, September 1961 - June 1962.
Research Assistant, with Dr. Harold C. Bold, Department of Botany, University of Texas at Austin, 1961-1964.
Research Associate with Dr. Wilson S. Stone, Hawaiian Drosophila Project, Summers 1964, 1965.
University Post Doctoral Fellow, Department of Botany, University of Texas at Austin, Summer 1965.
Assistant Professor, Department of Botany, University of Texas at Austin, September 1965 - August 1968.
National Science Foundation Post Doctoral Fellow, Division of Cell Biology, University of Freiburg, West Germany, September 1968 - August 1969.
Associate Professor, Department of Botany, University of North Carolina at Chapel Hill, September 1968 - June 1973.
Member, Laboratories for Reproductive Biology, University of North Carolina School of Medicine, 1970 - 1978.
Director, Electron Microscopy Laboratory, Department of Botany, University of North Carolina at Chapel Hill, September 1969 - June 1982.
Professor, Department of Botany, University
of North Carolina at Chapel Hill, June
1973 - June 1982.
Visiting Fellow, Department of Developmental Biology, Research School of Biological Sciences, The Australian National University, Canberra, Australia, January - August 1981.
Professor, Department of Botany, The University of Texas at Austin, July 1982 - Present.
Johnson & Johnson Centennial Chair in Plant Cell Biology, The University of Texas at Austin, September, 1982 - Present.
5. MEMBERSHIPS IN PROFESSIONAL SOCIETIES
Phycological Society of America
The Fiber Society
A.A.A.S.
American Society for Cell Biology
Microscopy Society of America
Sigma Xi
American Chemical Society
Cellulose, Paper and Textile Division (ACS)
Division of Polymer Chemistry (ACS)
American Society of Plant Physiologists
Botanical Society of America
International Society for Plant Molecular Biology
American Society for Gravitational and Space Biology
6. HONORS, AWARDS,AND ELECTED MEMBERSHIPS
Darbaker Prize in Phycology, July 1978.
Lamb Award, University of Nebraska. 1980.
Anselme Payen Award, American Chemical Society, 1986.
Fellow, The International Academy of Wood Science, August, 1983 - present.
Senior Research Fellow - IC2 Institute, 1986-present.
President, Sigma Xi (University of North Carolina Chapter), 1981-1982.
Fellow, Japanese Society for the Promotion of Science - Japan, May-June, 1992.
7. EDITORIAL RESPONSIBILITIES
Editorial Boards:
Transactions of the American Microscopical Society, 1972-1974.
Protoplasma 1990-1997
Cellulose 1993-present
Advisory Boards:
Cellulose Chemistry and Technology 1991- present
Protoplasma, 1986.
8. STUDENTS
51 undergraduate students with research projects, 1974-present.
18 Ph.D. students completed, 1968-present.
12 Masters students completed, 1969-present.
16 Post-doctoral fellows, 1972-present.
41 Visiting faculty, 1970-present.
9. GRANTS
Research Grants from 1963 to present totaling $3,524,618.00.
10. PATENTS
Cellulose-synthetic Composite Fibers. 1980. The University of North Carolina, U.S. Patent #4,378,431.
Production of Microbial Cellulose. Roberts, Hardison, and Brown. 1984. The University of Texas at Austin. U.S. Patent Application Serial No. 684,844. UT/AUS:137.
Magnetic Alteration of Cellulose During its Biosynthesis. Brown, Brown, and Gretz. Submitted, April 1985. The University of Texas at Austin. U.S. Patent Application Serial No. 719,505. UT/AUS:145.
Use of Cellulose Preparations in the Cultivation of Cellulose-Producing Microorganisms. Brown. Submitted, August 1986. The University of Texas at Austin. U.S. Patent Application Serial No. 900,384. UT/AUS:170.
Microbial Cellulose Modified during Synthesis. Brown. Submitted, March 1987. The University of Texas at Austin. U.S. Patent Application Serial No. 022,904. UT/AUS:179.
Multi-ribbon Microbial Cellulose. Brown and Lin. Submitted, March 1987. The University of Texas at Austin. U.S. Patent Application Serial No. 023,336. UT/AUS:233.
In vivo Biosynthesis of Cellulose II. Brown, Roberts and Saxena. Submitted May 1988. The University of Texas at Austin. U.S. Patent Application Serial No. 198,784. UT/AUS:302.
High Resolution Replicas. Brown and Mizuta. Submitted July, 1988. The University of Texas at Austin. UT/AUS:351.
Recombinant Cellulose Synthase. I. Saxena, F.C. Lin, and R. M. Brown, Jr. Submitted. 1990. The University of Texas at Austin. UT/AUS:441.
Synthetic Cellulose I Production . J. Lee, S. Kobayashi, S. Shoda, S. Kuga, K. Kudlicka, K. Okuda, L. Li, and R. M. Brown, Jr. Submitted 1993. Owned by Inventors.
11. BOOKS
Brown, R.M., Jr. and H.C. Bold. Phycological Studies V. Comparative Studies of the Algal Genera Tetracystis and Chlorococcum. Univ. of Texas Publ. No. 6417, 213 pp.
Parker, B.C. and R.M. Brown, Jr., ed. 1971. Contributions in Phycology. Allen Press, Lawrence, Kansas. 189 pp.
Brown, R.M., Jr. ed. 1982. Cellulose and Other Natural Polymer Systems: Biogenesis, Structure, and Degradation. Plenum Publ. Corp., New York.
12. PUBLICATIONS
1. Brown, R.M., Jr. and H.W. Bischoff. 1962. A new and useful method for obtaining axenic cultures of algae. Phycol. News. Bull. 15:43-44.
2. McElhenny, T.R., H.C. Bold, R.M. Brown, Jr. and J.P. McGovern. 1962. Algae: a cause of inhalant allergy in children. Ann. Allergy 20:739-743.
3. Brown, R.M., Jr., D.A. Larson, and H.C. Bold. 1964. Airborne algae: their abundance and heterogeneity. Science 143:583-585.
4. McGovern, J.P., T.R. McElhenny, and R.M. Brown, Jr. 1965. Airborne algae and their allergencity. Part I. Air sampling and delineation of the problem. Ann Allergy 23:47-50.
5. Smith, K.M. and R.M. Brown, Jr. 1965. Replication cycle of a Granulosis virus. Nature 207:106-107.
6. Brown, R.M., Jr. and R.N. Lester. 1965. Comparative immunology of the algal genera Tetracystis and Chlorococcum. J. Phycol. 2:60-65.
7. Smith, K.M. and R.M. Brown, Jr. 1965. A study of the long virus rods associated with insect granulosis. Virology 27:512-519.
8. Brown, R.M., Jr., K.M. Smith, and P.L. Walne. 1966. The replication cycle of the blue-green algal virus LPP-1. Nature 212:729-730.
9. Smith, K.M., R.M. Brown, Jr., D. Goldstein, and P.L. Walne. 1966. Culture methods for the blue-green alga Plectonema boryanum and its virus, with an electron microscope study of virus-infected cells. Virology 28:580-591.
10. Smith, K.M., R.M. Brown, Jr., and P.L. Walne. 1966. Electron microscopy of the infection process of the blue-green alga virus. Virology 30:182-192.
11. Smith, K.M., R.M. Brown, Jr., and P.L. Walne. 1967. Ultrastructural and time-lapse studies on the replication cycle of the blue-green algal virus LPP-1. Virology 31:329-337.
12. Brown, R.M., Jr., and P.L. Walne. 1967. Comparative immunology of selected wild types, varieties, and mutants of Chlamydomonas. J. Protozool. 14:365-373.
13. Arnott, H.J. and R.M. Brown, Jr. 1967. Ultrastructure of the eyespot and its possible significance in phototaxis in Tetracystis excentrica. J. Protozool. 14:529-539.
14. Brown, R.M., Jr., H.J. Arnott, T. Bisalputra, and L.R. Hoffman. 1967. The pyrenoid: its structure, distribution, and function. J. Phycol. 3(supp.), 5-7.
15. Brown, R.M., Jr., S.C. Johnson, and H.C. Bold. 1968. Electron microscopy and phase contrast microscopy of sexual reproduction in Chlamydomonas moewusii. J. Phycol. 4:100-125.
16. Brown, R.M., Jr. and R. Wilson. 1968. Ultrastructure of the lichen physcia aipolia (Ehrh) NYL. J. Phycol. 4:230-240.
17. Brown, R.M., Jr. 1969. Burnishing uncoated grids before mounting ultra-thin sections: a means of assuring adhesion. Stain Tech. 44:158.
18. Brown, R.M., Jr. 1969. Observations on the relationship of the Golgi apparatus to wall formation in the marine chrysophycean alga, Pleurochrysis scherffelii. J. Cell Biol. 41:109-123.
19. Brown, R.M., Jr. and R.J. McLean. 1969. New taxonomic criteria in classification of Chlorococcum species. II. Pyrenoid structure. J. Phycol. 5:114-118.
20. Franke, W.W., S. Krien, and R.M. Brown, Jr. 1969. Simultaneous glutaraldehyde osmium tetroxide fixation with postosmication: an improved fixation procedure for electron microscopy of plant and animal cells. Histochemie 19:162-164.
21. Stewart, J. and R.M. Brown, Jr. 1969. Cytophaga that kills or lyses algae. Science 164:1523-1524.
22. Brown, R.M., Jr., W.W. Franke, H. Kleinig, H. Falk, and P. Sitte. 1969. A cellulosic wall component produced by the Golgi apparatus. Science 166:894-896.
23. Van Baalen, C. and R.M. Brown, Jr. 1969. The ultrastructure of the marine blue-green alga Trichodesmium erythraeum, with special reference to the cell wall, gas vacuoles, and cylindrical bodies. Archiv. f. Mikrobiol. 69:79-91.
24. Brown, R.M., Jr., W.W. Franke, H. Kleinig, H. Falk, and P. Sitte. 1970. Scale formation in chrysophycean algae. I. Cellulosic and non-cellulosic wall components made by the Golgi apparatus. J. Cell Biol. 45:246-271.
25. Brown, R.M., Jr. and C. Van Baalen. 1970. Comparative ultrastructure of a filamentous mutant and the wild type of Agmenellum quadruplicatum. Protoplasma 70:87-99.
26. Brown R.M., Jr. and H.J. Arnott. 1970. Structure and function of the algal pyrenoid. I. Ultrastructure and cytochemistry during zoosporogenesis of Tetracystis excentrica. J. Phycol. 6:14-22.
27. Thomas, D.L. and R.M. Brown, Jr. 1970. New taxonomic criteria in the classification of Chlorococcum species. III. Isoenzyme analysis. J. Phycol. 6:293-299.
28. Thomas, D.L. and R.M. Brown, Jr. 1970. Isoenzyme analysis and morphological variation of thirty-two isolates of Protosiphon. Phycologia 9:285-292.
29. Brown, R.M., Jr. and H.J. Arnott. 1971. A photographic method for producing true three-dimensional electron micrographs. Protoplasma 72:105-108.
30. Brown, R.M., Jr. 1971. The distribution of airborne algae and fern spores across the island of Oahu, Hawaii. IN: Contributions in Phycology (B.C. Parker and R.M. Brown, Jr., eds.). Allen Press, Lawrence, Kansas. pp. 175-188.
31. Schnepf, E. and R.M. Brown, Jr. 1971. On relationships between endosymbiosis and the origin of plastids and mitochondria. IN: Origin and Development of Cell Organelles (Ursprung and Reinert, eds.). Springer-Verlag.
32. Brown, R.M., Jr. and W.W. Franke. 1971. A microtubular crystal associated with the Golgi field of Pleurochrysis scherffelii. Planta 96:354-363.
33. Franke, W.W. and R.M. Brown, Jr. 1971. Scale formation in chrysophycean algae. III. Negatively stained scales of the coccolithophorid Hymenomonas. Archiv. f. Mikrobiol. 77:12-19.
34. Stewart, J.R. and R.M. Brown, Jr. 1971. Algicidal nonfruiting myxobacteria with high G+C ratios. Archiv. f. Mikrobiol. 80:176-190.
35. Brown, R.M., Jr., 1071. Studies of Hawaiian fresh-water and soil algae. I. the atmospheric dispersal of algae and fern spores across the island of Oahu, Hawaii. Contributions in Phycology. Sept. 1971, 175-188.
36. Brown, R.M., Jr. Algal Viruses. 1972. IN: Advances in Virus Research 17:243-274. Academic Press, New York.
37. Ellis, E.A. and R.M. Brown, Jr. 1972. Freeze etch electron microscopy of the lichen, Parmelia caperata. Trans. Amer. Microscop. Soc. 91:411-421.
38. Herth, W., W.W. Franke, J. Stadler, H. Bittiger, G. Keilich, and R.M. Brown, Jr. 1972. Scale formation in chrysophycean algae. IV. Further characterization of the alkali-stable material from the scales of Pleurochrysis scherffelii: a cellulosic glycoprotein. Planta 105:79-92.
39. Brown, R.M., Jr. 1972. Atmospheric transport of algae in Hawaii. IN: Proceedings Workshop/Conference I. Ecological systems approaches to aerobiology. I. Identification of component elements and their function relationships. U.S. IBP Handbook #2 (W.S. Benninghoff and R.L. Edmonds, eds.). pp. 133-136.
40. Ott, D. and R.M. Brown, Jr. 1972. Light and electron microscopical observations on mitosis in Vaucheria litorea. Hofman Ed. C. Agardh. British Phycol. J. 7:361-374.
41. Schlichting, H.E., Jr., R.M. Brown, Jr. and P.E. Smith. 1973. Airborne
algae of Hawaii: a model for coordinated aerobiological research. IN: Proceeding
Workshop/
Conference I. Ecological systems approaches to aerobiology.
II. Development, demonstration, and evaluation of models. U.S. IBP Handbook
#3 (W.S. Benninghoff and R.L. Edmonds, eds.). pp. 150-155.
42. Brown, R.M., Jr., W. Herth, W. Franke, and D. Romanovicz. 1973. The role of Golgi apparatus in the biogenesis and secretion of a cellulosic glycoprotein in Pleurochrysis: a model system for th synthesis of structural polysaccharides. IN: Biogenesis of Plant Cell Wall Polysaccharides. . (F. Loewus, ed.). Academic Press. p. 207-258.
43. Brown, R.M., Jr. 1974. Bewegung des Protoplasten und Funktion des Golgi-Apparates in Algen. Film C. 1071/1971 des Inst. Wiss. Film, Göttingen, Publikationen zu Wissenschaftlicher Film 7:361-381.
44. Ott, D.W. and R.M. Brown, Jr. 1974. Developmental cytology of the genus Vaucheria. I. Organization of the vegetative filament. British Phycol J. 9:111-126.
45. Ott, D.W. and R.M. Brown, Jr. 1974. Developmental cytology of the genus Vaucheria. II. Sporogenesis in V. fontinalis. British Phycol J. 9:333-351.
46. McLean, R.J., C.J. Laurendi, and R.M. Brown, Jr. 1974. The relationship of gamone to the mating reaction in Chlamydomonas meowusii. Proc. Nat. Acad. Sci. U.S.A. 71:2610-2613.
47. Ott, D.W. and R.M. Brown, Jr. 1974. Cell surface differentiation of Chlamydomonas during gametogenesis. Devel. Biol. 36:279-285.
48. Triemer, R.E. and R.M. Brown, Jr. 1974. Cell division in Chlamydomonas meowusii. J. Phycol. 10:419-433.
49. Brown, R.M., Jr. 1974. The Golgi apparatus and endomembrane system; its role in the biosynthesis, transport, and secretion of cell wall constituents in Pleurochrysis. International Symposium on Plant Cell Differentiation. Lisbon, Portugal, August 1974 (M.S. Pais, ed.). Portugal Acta Biologica 14:369-384.
50. McLean, R.J., C.J. Laurendi, and R.M. Brown, Jr. 1974. The relationship of gamone to the mating reaction in Chlamydomonas moewusii. Proc. Nat. Acad. Sci. U.S.A. 71(7):2610-2613.
51. Triemer, R.E. and R.M. Brown, Jr. 1975. Ultrastructure of fertilization in Chlamydomonas moewusii. Protoplasma 84:315-325.
52. Herth, W., A. Kuppel, W. Franke, and R.M. Brown, Jr. 1975. The ultrastructure of the scale cellulose from Pleurochrysis scherffelii under various experimental conditions. Cytobiologie 10:268-284.
53. Ott, D.W. and R.M. Brown, Jr. 1975. Developmental cytology of the genus Vaucheria. III. Emergence, settlement, and germination of the mature zoospore of V. fontinalis. (L.) Christensen. British Phycol. J. 10:49-56.
54. Triemer, R.E. and R.M. Brown, Jr. 1975. Fertilization in Chlamydomonas reinhardi, with special reference to the structure, development, and fate of the choanoid body. Protoplasma 85:99-107.
55. Brown, R.M. Jr. 1975. Pyrobotrys gracilis (Volvocales) vegetative development. Encyclopaedia Cinematographica. Film E 1678 des Inst. Wiss. Film Göttingen Research Film 8:488-492.
56. Brown, R.M., Jr. 1975 Pleurochrysis scherffelii (Haptophyceae). Vegetative development. Encyclopaedia Cinematographica. Film E 1682 des Inst. Wiss. Film, Göttingen. Research Film 8:491-500.
57. Brown, R.M., Jr. 1975. Cyanophycean virus LPP-1. Cytopathic effects in Plectonema boryanum. Encyclopaedia Cinematographica. Film E 1746 des Inst. Wiss. Film, Göttingen. Research Film 8:494-502.
58. Brown, R.M., Jr. and D.K. Romanovicz. 1976. Biogenesis and structure of Golgi-derived cellulosic scales in Pleurochrysis. I. Role of the endomembrane system in scale assembly and exocytosis. Applied Polymer Symp. 28:537-585. John Wiley & Sons, Inc., New York.
59. Romanovicz, D.K. and R.M. Brown, Jr. 1976. Biogenesis and structure of Golgi-derived cellulosic scales in Pleurochrysis. II. Identification of the scale subcomponents, with reference to cytochemical enzyme localization and the supermolecular structure of the cellulosic microfibril. Applied Polymer Symp. 28:587-610. John Wiley & Sons, Inc., New York.
60. Carson, J.L. and R.M. Brown, Jr. 1976. The correlation of soil algae, airborne algae, and fern spores with meteorological conditions on the island of Hawaii. Pacific Science 30(2):197-205.
61. Westafer, J.M. and R.M. Brown, Jr. 1976. Electron microscopy of the cotton fiber: new observations on cell wall formation. Cytobios. 15:111-138.
62. Brown, R.M., Jr. and D. Montezinos. 1976. Cellulose microfibrils: visualization of biosynthetic and orienting complexes in association with the plasma membrane. Proc. Nat. Acad. Sci. U.S.A. 73:143-147.
63. Triemer, R.E. and R.M. Brown, Jr. 1976. Ultrastructural studies of meiosis in Chlamydomonas reinhardi. British Phycol. J. 12:33-44.
64. Montezinos, D. and R.M. Brown, Jr. 1976. Surface architecture of the plant cell: biogenesis of the cell wall, with special emphasis on the role of the plasma membrane in cellulose biosynthesis. J. Supramol. Structure 5:277-290.
65. Mueller, S., R.M. Brown, Jr. and T.K. Scott. 1976. Cellulosic microfibrils: nascent stages of synthesis in a higher plant cell. Science 194:949-951.
66. Brown, R.M., Jr., J.H.M. Willison, and C.L. Richardson. 1976. Cellulose biosynthesis in Acetobacter xylinum: 1. Visualization of the site of synthesis and direct measurement of the in vivo process. Proc. Nat. Acad. Sci. U.S.A. 73(12):4565-4569.
67. Brown, R.M., Jr. 1976. Phototaxis der Grünalge Pyrobotrys. Institut für den Wissenschaftlichen film. Wissenschaftlichen Film C 1171/1975 p 3-18. Göttingen.
68. Brown, R.M., Jr. and J.H.M. Willison. 1977. Golgi apparatus and plasma membrane involvement in secretion and cell surface deposition. Proc. First Int. Cong. Cell Biol. (Boston). IN: International Cell Biology 1976. (B.R. Brinkley and K.R. Porter, eds.). Rockefeller University Press. pp. 267-283.
69. Willison, J.H.M. and R.M. Brown, Jr. 1977. An examination of the developing cotton fiber: wall and plasmalemma. Protoplasma 92:21-41.
70. Ott, D.W. and R.M. Brown, Jr. 1978. Developmental cytology of the genus Vaucheria. IV. Spermatogenesis. British Phycol J. 13:69-85.
71. Willison, J.H.M. and R.M. Brown, Jr. 1978. Cell wall structure and deposition in Glaucocystis. J. Cell Biol. 77:103-119.
72. Carson, J.L. and R.M. Brown, Jr. 1978. Studies of Hawaiian freshwater and soil algae. II. Colonization and succession of algae on dated volcanic substrates. J. Phycol. 14(2):171-178.
73. Sherman, L. and R.M. Brown, Jr. 1978. Cyanophages and viruses of eukaryotic algae. IN: Comprehensive Virology 12:145-234. Plenum Press, New York.
74. Willison, J.H.M. and R.M. Brown, Jr. 1978. A model for the pattern of microfibrils in the cell wall of Glaucocystis. Planta 141:51-58.
75. Niklas, K.J., R.M. Brown, Jr., R. Santos, and B. Vian. 1978. Ultrastructure and cytochemistry of Miocene angiosperm leaf tissues. Proc. Nat. Acad. Sci. U.S.A. 75:3263-3267.
76. Montezinos, D. and R.M. Brown, Jr. 1979. Cell wall biogenesis in Oocystis: experimental alteration of microfibril assembly and orientation. Cytobios 23:119-139.
77. Kavookjian, A.M.A. and R.M. Brown, Jr. 1979. Antigenic properties of the Golgi derived scales of Pleurochrysis scherffelii. Cytobios 23:45-70.
78. Spiegel, F.W., L.S. Olive, and R.M. Brown, Jr. 1979. Roles of action during sporocarp culmination in the simple mycetozoan Planoprotostelium aurantium. Proc. Nat. Acad. Sci. U.S.A. 76(5):2335-2339.
79. Vian, B., S. Mueller, and R.M. Brown, Jr. 1979. A freeze-etching and replication study of wall deposition in elongating plant cells. Cytobios 22:7-15.
80. Willison, J.H.M. and R.M. Brown, Jr. 1979. Pretreatment artifacts in plant cells. IN: Freeze Fracture: Methods, Artifacts and Interpretations. John E. Rash and C. Sue Hudson (eds.) Raven Press, New York, NY. pp.51-57.
82. Mueller, S.C. and R.M. Brown, Jr. 1980. Evidence for an intramembranous component associated with a cellulose microfibril synthesizing complex in higher plants. J. Cell Biol. 84:315-326.
83. Haigler, C., R.M. Brown, Jr. and M. Benziman. 1980. Calcofluor White ST alters the in vivo assembly of cellulose microfibrils. Science 210:903-906 (cover).
84. Benziman, M., C.H. Haigler, R.M. Brown, Jr., A.R. White, and K.M. Cooper. 1980. Cellulose biogenesis: polymerization and crystallization are coupled processes in Acetobacter xylinum. Proc. Nat. Acad. Sci. U.S.A. 77:6678-6682.
85. Willison, J.H.M., R.M. Brown, Jr., and S.C. Mueller. 1980. A critical examination of the electron-microscopical evidence in green plants. J. Microsc. 118:177-186.
86. White, A.R., and R.M. Brown, Jr. 1981. Enzymatic hydrolysis of cellulose: visual characterization of the process. Proc. Nat. Acad. Sci. U.S.A. 78:1047-1051.
87. Brown, R.M., Jr. 1981. Integration of biochemical and visual approaches to the study of cellulose biosynthesis and degradation. IN: Biosynthesis and biodegradation of wood components. The Ekman-Days 1981 International Symposium on Wood and Pulping Chemistry. Vol. 3, pp. 3-15.
88. White, A.R. and R.M. Brown, Jr. 1981. Correlation of biochemical and visual evidence of enzymatic cellulose degradation. IN: Biosynthesis and biodegradation of wood components. The Ekman-Days 1981 International Symposium on Wood and Pulping Chemistry. Vol. 5, pp. 44-46.
89. Haigler, C.H. and R.M. Brown, Jr. 1981. Probing the relationship of polymerization and crystallization in the biogenesis of cellulose I. IN: Biosynthesis and biodegradation of wood components. The Ekman-Days 1981 International Symposium on Wood and Pulping Chemistry, Vol. 5, pp. 14-16.
90. McLean, R.J., K.R. Katz, N.J. Sedita, A.L. Menoff, C.J. Laurendi, and R.M. Brown, Jr. 1981. Dynamics of concanavalin A binding sites in Chlamydomonas moewusii flagellar membranes. Ber. Deutsch. Bot. Ges. Bd. 94:387-400.
91. Niklas, K.J., and R.M. Brown, Jr. 1981. Some chemophysical factors attending fossilization. Bioscience 31(2):148-149.
92. Mueller, S.C. and R. M.Brown, Jr. 1982. The control of cellulose microfibril deposition in the cell wall of higher plants. I. Planta 154:489-500.
93. Mueller, S.C. and R. M. Brown, Jr. 1982. The control of cellulose microfibril deposition in the cell wall of higher plants. II. Planta 154:501-515.
94. Haigler, C.H., A.R. White, R.M. Brown, Jr. and K.M. Cooper. 1982. Alteration of in vivo cellulose ribbon assembly by carboxymethyl-cellulose and other cellulose derivatives. J. Cell Biol. 94:64-69.
95. Brown, R.M. Jr., C.H. Haigler, and K. Cooper. 1982. Experimental induction of altered nonmicrofibrillar cellulose. Science 218:1141-1142.
96. Roberts, E., R.W. Seagull, C. Haigler, and R.M. Brown, Jr. 1982. Alteration of cellulose microfibril formation in eukaryotic cells: Calcofluor White interferes with microfibril assembly and orientation in Oocystis apiculata. Protoplasma 113:1-9.
97. Mueller, S.C., G.A. Maclachlan, and R.M. Brown, Jr. 1983. Cellulose microfibril assembly and orientation in higher plant cells. Journal of Applied Polymer Science: Applied Polymer Symposium 37:79-90.
98. Brown, R.M. Jr., C.H. Haigler, J. Suttie, A.R. White, E. Roberts, C. Smith, T. Itoh, and K. Cooper. 1983. The biosynthesis and degradation of cellulose. Journal of Applied Polymer Science: Applied Polymer Symposium 37:33-78.
99. Itoh, T. and R.M. Brown, Jr. 1984. The assembly of cellulose microfibrils in Valonia macrophysa. Planta 160:372-381.
100. Itoh, T., R.M. O'Neil, and R.M. Brown, Jr. 1984 Interference of cell wall regeneration of Boergesenia forbesii protoplasts by Tinopal LPW, a fluorescent brightening agent. Protoplasma 123:174-183.
101. Brown, R.M. Jr. 1985. John Innes Symposium. Cellulose microfibril assembly and orientation: Recent developments. Journal of Cell Science Suppl. 2:13-32.
102. Brown, R.M. Jr. 1985. The microbial synthesis of cellulose. IN: BIOEXPO85: 325-335. Published by Kahners Exposition Group, Boston, Massachusetts.
103. Lin, F.C., R.M. Brown, Jr., J. Cooper, and D. Delmer. 1985. Synthesis of fibrils in vitro by a solubulized cellulose synthase from Acetobacter xylinum. Science 230: 822-825.
104. Haigler, C., R.M. Brown, Jr. 1985. Transport of rosettes from the Golgi apparatus to the plasma membrane in isolated mesophyll cells of Zinnia elegans during differentiation. Protoplasma 134:111-120.
105. Brown, R.M., Jr. 1985. Biogenesis of cellulose. Discovery 9(4):18-23.
106. Itoh, T., R. Legge, and R.M. Brown, Jr. 1986. The effects of selected inhibitors on cellulose microfibril assembly in Boergesenia forbesii protoplasts. J. Phycol. 22:224-233.
107. Kudlicka, K., A. Wardrop, T. Itoh, and R.M. Brown, Jr. 1987. Further evidence from sectioned material in support of a linear terminal complex in cellulose synthesis. Protoplasma 136:96-103.
108. Lee, S.Y. and R.M. Brown, Jr. 1987. Experimental cell fusion with selected siphonocladalean algal cells. IN: Cell Fusion. Art Sowers, Ed. Plenum Press, New York, NY. pp 167-178.
109. Hayashi, T., S.M. Read, J. Bussell, M. Thelen, F.C. Lin, R.M. Brown, Jr. and D.P. Delmer. 1987. UDP-Glucose (1-3)-b-Glucan synthesis from mung bean and cotton. Plant Physiology 83:1054-1062.
110. Hotchkiss, A.T., Jr. and R.M. Brown, Jr. 1987. The association of rosette and globule terminal complexes with cellulose microfibril assembly in Nitella translucens var. axillaris (Charophyceae). J. Phycol. 23:229-237.
111. Kuga, S. and R.M. Brown, Jr. 1987. Practical aspects of lattice imaging of cellulose. J. Electron Mic. Tech. 6:349-356.
112. Bureau, T.E. and R.M. Brown, Jr. 1987. In vitro synthesis of cellulose II from a cytoplasmic membrane fraction of Acetobacter xylinum, Proc. Nat. Acad. Sci. U.S.A. 84:6985-6989.
113. Brown, R.M., Jr. 1987. Sources of cellulose: A different perspective. IN: TAPPI Proc. Intl. Dis. Pulps Conference, Geneva. pp. 1-5.
114. Brown, R.M., Jr. 1987. The biosynthesis of cellulose. Food Hydrocolloids, 1(5/6):345-351.
115. Kuga, S. and R.M. Brown, Jr. 1987. Lattice imaging of Ramie cellulose. Polymer Communications 28:311-314.
116. Folsom, D.B. and R.M. Brown, Jr. 1987. Changes in cellulose microfibril orientation during differential growth in oat coleoptiles. IN: Physiology of Cell Expansion During Plant Growth. D.J. Cosgrove and D.P. Knievel, Eds. Amer. Soc. Plant Physiologists.pp 58-73.
117. Legge, R.L. and R.M. Brown, Jr. 1988 Modification of protoplast cell wall regeneration by membrane perturbation. Protoplasma 143:38-42.
118. Kiss, J., E. Roberts, R.M. Brown, Jr. and R. Triemer. 1988. X-ray and dissolution studies of paramylon from Euglena. Protoplasma. 146:150-146.
119. Kuga, S. and R.M. Brown, Jr. 1988. Silver labeling of the reducing ends of bacterial cellulose. Carbohydrate Research 180:345-350.
120. Hayano, W., T. Itoh, and R.M. Brown, Jr. 1988. Orientation of microtubules during regeneration of cell walls in selected giant marine algae. Plant Cell Physiology 29(5):785-793.
121. Itoh, T. and R.M. Brown, Jr. 1988. Development of cellulose synthesis in Boergesenia and Valonia. Protoplasma 144:160-169.
122. Brown, R.M., Jr. 1988. Use of Kodak Tri-X pan film and Kodak T-Max 40 professional film in the recording of lattice images of labile specimens with electron microscopy. Tech Bits, Spring 1988, pp. 9-11.
123. Hotchkiss, A.T. and R.M. Brown, Jr. 1988. Evolution of the cellulosic cell wall in the Charophyceae. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., pp. 591-609.
124. Hotchkiss, A.T., Jr., M.R. Gretz, K.B. Hicks, and R.M. Brown, Jr. 1989. The composition and phylogenetic significance of the Mougeotia (Charophyceae) cell wall. Journal of Phycology.25:646-654.
125. Delgado, R.M. III., M.J. Fink, and R.M. Brown, Jr. 1989. Imaging of submicron objects with the light microscope. Proc. Royal Mic. Soc. London. 154(2):129-141.
126. Brown, R.M., Jr. 1989. Cellulose biogenesis and a decade of progress: a personal perspective. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 639-657.
127. Mizuta, S., E.M. Roberts, and R.M. Brown, Jr. 1989. A new cellulose synthesizing complex in Vaucheria hamata and its relation to microfibril assembly. In- Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 659-676.
128. Lin, F.C. and R.M. Brown, Jr. 1989. Purification of cellulose synthase from Acetobacter xylinum. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 473-492.
129. White, D.G. and R.M. Brown, Jr. 1989. Prospects for the commercialization of the biosynthesis of microbial cellulose. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 573-590.
130. Saxena, I.M. and R.M. Brown, Jr. 1989. Study of cellulose biosynthesis in Acetobacter xylinum: a genetic approach. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 537-557.
131. Kuga, S. and R.M. Brown, Jr. 1989. Correlation between structure and biogenic mechanisms of cellulose: new insights based on recent electron microscopical findings. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 677-688.
132. Roberts, E.M., I.M. Saxena, and R.M. Brown, Jr. 1989. Biosynthesis of cellulose II. In: Cellulose and Wood - Chemistry and Technology, Ed. C. Schuerch. John Wiley and Sons, Inc. N.Y., 689-704.
133. Gretz, M.R., D.B. Folsom, and R.M. Brown, Jr. 1989. Cellulose biogenesis in bacteria and higher plants is disrupted by magnetic fields. Naturwissenschaften. 76: 380-383
134. Brown, R.M., Jr. 1989. Bacterial cellulose. In: Cellulose:Structural and Functional Aspects, Ed Kennedy, Phillips, & Williams. Ellis Horwood Ltd. pp 145-151.
135. Mizuta, S., U. Kurogi, K. Okuda, and R. M. Brown, Jr. 1989. Microfibrillar structure, cortical microtubule arrangement and the effect of amiprophos -methyl on microfibril orientation in the thallus cells of the filamentous green alga, Chamaedoris orientalis. Annals of Botany 64:383-394.
136. Brown, Jr. R. M. 1989. Advances in Cellulose Biosynthesis. IN: Assessment of Biobased Materials Ed. H.C. Chum. SERI/TR-234-3610. U.S. Department of Energy. pp 9-1 to 9-7.
137. Lin, F.C., R. M. Brown, Jr., R. P. Drake, Jr., and B.E. Haley. 1990. Identification of the uridine 5'-diphosphoglucose (UDP-glc) binding subunit of cellulose synthase in Acetobacter xylinum using the photoaffinity probe 5-azido-UDP-glc. J. Biol. Chem. 265: 4782-4784.
138. Brown, Jr. R. M. 1990. Algae as tools in studying the biosynthesis of cellulose, nature's most abundant macromolecule. In: Experimental Phycology l: Cell walls and Surfaces, Reproduction, Photosynthesis Ed:Wiessner, Robinson, and Starr. Springer-Verlag Berlin pp 20-39.
139. Saxena, I. M., F. C. Lin, and R. M. Brown, Jr. 1990. Cloning and sequencing ofthe cellulose synthase catalytic subunit gene of Acetobacter xylinum. Plant Molecular Biology 15:673-683.
140. Smotkin, E. S., R. M. Brown, Jr., L. K. Rabenberg, K. Salomon, A. J. Bard, A. Campion, M. A. Fox, T. E. Mallouk, S. E. Webber, and J. M. White.1990. Ultrasmall particles of CdSe and CdS formed in Nafion by an ion dilution technique. J. Phys. Chem.94:7543-7549.
141. Saxena, I. M. , F. C. Lin, and R. M. Brown, Jr. l99l. Identification of a new gene in an operon for cellulose biosynthesis in Acetobacter xylinum. Plant Molecular Biology 169:947-954.
142. Kuga, S. and R. M. Brown, Jr. 1991. Physical Structure of Cellulose Microfibrils: Implications for Biogenesis. In: Biosynthesis and Biodegradation of Cellulose Ed. C.H. Haigler and P.J. Weimer. Marcel Dekker, Inc. New York. pp 125-142.
143. Mizuta, S. and R. M. Brown, Jr. 1992. High resolution analysis of the formation of cellulose synthesizing complexes in Vaucheria hamata. Protoplasma 166: 187-199.
144. Mizuta, S. and R. M. Brown, Jr. 1992. Effects of 2,6- dichlorobenzonitrile and Tinopal LPW on the structure of the cellulose synthesizing complexes of Vaucheria hamata. Protoplasma 166:200-207.
145. Okuda, K. and Brown, Jr. R.M. 1992. A new putative cellulose-synthesizing complex of Coleochaete scutata. Protoplasma 168:51-63.
146. Brown, Jr. R. M. 1992. Emerging technologies and future prospects for industrialization of microbially derived cellulose. In: Harnessing Biotechnology for the 21st Century Ed. M.R Ladisch and A Bose. Proceedings of the Ninth International Biotechnology Symposium and Exposition. Crystal City, Virginia. American Chemical Society, Washington, D.C. pp 76-79.
147. Drake, Jr. R. R. , Li, L. and R. M. Brown, Jr. 1992. Photoaffinity labeling of cellulose synthases. Cotton Fiber Cellulose: Structure, Function and Utilization Conference. Proceedings pp 163-170.
148. Brown, Jr., R. M. , K. Kudlicka, S. K.Cousins, and R. Nagy. 1993. Gravity effects on cellulose assembly. Amer. J.Bot. 79: 1247-1258.
149. Okuda K., Li L., Kudlicka K., Kuga S., Brown R. M. Jr. 1993. ß-glucan synthesis in the cotton fiber. I. Identification of ß-1,4- and ß-1,3- glucans synthesized in vitro . Plant Physiol. 101: 1131-1142.
150. Li L., Brown R.M. Jr. 1993. ß-glucan synthesis in the cotton fiber. II. Regulation and kinetic properties of ß-glucan synthases. Plant Physiol. 101: 1143-1148.
151. Li L., Drake R. R. Jr., Clement S., Brown R. M. Jr. 1993. ß-glucan synthesis in the cotton fiber. III. Identification of UDP-glu-binding components of ß-glucan synthases by photoaffinity labeling with [ß 32P]-5'N3-UDP-glucose. Plant Physiol. 101: 1149-1156.
152. Kuga, S., S. Takagi, and R. M. Brown, Jr. 1993. Native folded-chain cellulose II. Polymer 34:3293-3297.
153. Kobayashi, S., S. Shoda, J.H. Lee, K. Okuda, and R. M. Brown, Jr. 1994. Direct visualization of synthetic cellulose formation via enzymatic polymerization using transmission electron microscopy. 1994. Macromol. Chem. Phys. 195: 1319-1326.
154. Brown, Jr., R. M., L. Li, K. Okuda, S. Kuga, K. Kudlicka, R. Drake, R. Santos, and S. Clement. 1994. Viewpoints: A Reply. In vitro cellulose synthesis in plants. Plant. Physiol. 101: 1-2.
155. Lee, J. H., R. M. Brown, Jr., S. Kuga, S. Shoda, and S. Kobayashi. 1994. The first assembly of synthetic cellulose I. Proc. Natl Acad. Sci. U.S.A. 91:7425-7429.
156. Okuda, K., I. Tsekos, and R. M. Brown, Jr. 1994. Cellulose microfibril assembly in Erythrocladia subintegra Rosenv.: an ideal system for understanding the relationship between synthetizing complexes (TCs) and microfibril crystallization. Protoplasma. 180: 49-58.
157. French, A.D., M.K. Dowd, S.K. Cousins, R. M. Brown, Jr., and D.P. Miller. 1994 Molecular deformation and lattice energies of models of solid saccharides. ACS Proceedings, 1994 San Diego Meetings
158. Saxena,. I.M., K.Kudlicka, K. Okuda, and R. M. Brown, Jr. 1994. Characterization of genes in the cellulose synthesizing operon (acs operon) of Acetobacter xylinum: Implications for cellulose crystallization. J. Bacteriology 176: 5735-5752.
159. Brown, Jr. R. M. 1994. Understanding nature's preference for cellulose
I assembly: Toward a new biotechnology era for cellulose. Proc. Inter.Symp.
Fiber Sci. and Tech. p437-439. Publishers. The Society of Fiber Science
and Technology, Japan
160. Brown, Jr. R. M. 1995. A tribute to Herman Mark and his
influence on cellulose research at The University of Texas at Austin. 1994.
Cellulose Chemistry & Technology. 29:525-532.
161. Kudlicka, K., R. M. Brown, Jr., L. Li, J. H. Lee, and S. Kuga.
1995. ß-glucan synthesis in the cotton fiber:
IV. In vitro assembly of the cellulose I allomorph. Plant
Physiology 107:111-123.
162. Kudlicka, K., Brown, Jr. R. M., Li, L., Lee, J. H., and S. Kuga. 1995. ß-glucan synthesis in the cotton fiber: IV. In vitro assembly of the cellulose I allomorph. Plant Physiology 107:111-123.
163. Saxena, I. M., Brown, Jr. R. M., Fevre, M., Geremia, R., and B. Henrissat. 1995. Multidomain architecture of glycosyl transferases: Implications for mechanism of action. J. Bacteriology. 177: 1419-1324.
164. Shibazaki, H., Kuga, S., Onabe, F., and R. M. Brown, Jr. 1995. Acid hydrolysis behaviour of microbial cellulose II. Polymer 36: 4971-4976.
165. French, A. D., Dowd, M. K., Cousins, S. K., Brown, Jr. R. M., and D. P. Miller. 1995. Molecular deformation and lattice energies of models of solid saccharides. In "Enzymatic Degradation of Insoluble Carbohydrates: ACS Symposium Series 618" (Ed. John N. Saddler and Michael H, Penner); American Chemical Society, Washington, D.C. pp. 13-37.
166. Cousins, S. K., and R. M. Brown, Jr. 1995. Cellulose I microfibril assembly: computational molecular mechanics energy analysis favours bonding by van der Waals forces as the initial step in crystallization. Polymer 36: 3885-3888.
168. Brown, Jr., R. M. 1996. The biosynthesis of cellulose. Pure Appl. Chem. 10: 1345-1373.
169. Kudlicka, K., Lee, J. H., and R. M. Brown, Jr. 1996. A comparative analysis of in vitro cellulose synthesis from cell-free extracts of mung bean (Vigna radiata, Fabaceae) and cotton (Gossypium hirsutum, Malvaceae). American Journal of Botany 83: 274-284.
170. Chen, H. P. and R. M. Brown, Jr. 1996. Immunochemical studies of the cellulose synthase complex in Acetobacter xylinum. Cellulose 3:63-76.
171. Tsekos, I, K. Okuda, and R. M. Brown, Jr. 1996.The formation and development of cellulose-synthesizing linear terminal complexes (TCs) in the plasma membrane of the marine red alga Erythrocladia subintegra Rosenv. Protoplasma 193:33-45.
172. Cousins, S. K. and R. M. Brown, Jr. 1997. X-ray diffraction
and ultrastructural analyses of dye-altered celluloses support van der
Waals forces as the initial step in cellulose crystallization. Polymer.
38:897-902
173. Cousins, S. K., and R. M. Brown, Jr. 1997. Photoisomerization
of a dye-altered b-1, 4 glucan sheet induces the crystallization of a cellulose-composite.
Polymer 38:903-912
174. Saxena, I. M. and R. M. Brown, Jr. 1997. Identification of cellulose synthase(s) in higher plants: Sequence analysis of processive b-glycosyltransferases with the common motif "D, D, D35Q(R,Q)XRW." Cellulose 4:33-49 (Note: click on "articles" then on Vol04, issue 01 to download a free pdf file of this article)
175. Kudlicka, K. and R. M. Brown, Jr. 1997. Cellulose and callose biosynthesis in higher plants. Plant Physiology 115:643-656.
23. ABSTRACTS
Author or co-author on more than 130 abstracts from 1961 until the present
